The influence of bronchial asthma control level on the quality of life indices

Authors

  • O. V. Herasymova National Pirogov Memorial Medical University, Vinnytsia, Ukraine,
  • T. L. Protsiuk National Pirogov Memorial Medical University, Vinnytsіa, Ukraine,
  • L. O. Protsiuk National Pirogov Memorial Medical University, Vinnytsia, Ukraine,
  • N. M. Surkova Vinnytsia Regional Children’s Clinical Hospital, Vinnytsia, Ukrainе,
  • L. D. Kotsur National Pirogov Memorial Medical University, Vinnytsіa, Ukraine,
  • O.V. Kuleshov National Pirogov Memorial Medical University, Vinnytsіa, Ukraine,

DOI:

https://doi.org/10.14739/2310-1237.2018.2.141394

Keywords:

bronchial asthma, quality of life, children

Abstract

Objective: to study the indices of general and specific quality of life in schoolchildren, depending on the level of bronchial asthma control.

Materials and methods: Quality of life parameters of 189 in-patients with BA, aged 6–17 years and 95 controls were studied. Parallel questioning with subsequent analysis of quality of life indices in 189 parents of BA children and 95 parents of the control group children was performed. General QL was evaluated using РedsQL (Pediatric Quality of Life Inventory 4.0). Specific quality of life was evaluated using specific quality of life questionnaire for the children ill with bronchial asthma – PAQLQ (Pediatric Asthma Quality of Life Questionnaire). Statistical analysis of the data obtained was done by variance statistical methods using the standard program package of multivariate statistical analysis Statistica 6.0

Results. The study found the index of physical functioning to be 43.6 [31.3–62.5] points in the children with UC BA, 53.1 [37.5–68.2] points in those with PC BA, being significantly lower as compared to the control group children – 79.6 [56.0–100.0] points (P < 0.001). Рhysical functioning index in the children with UC BA was 1.7 times lower as compared to those with C BA. Comparison of the indices in those with PC BA – 53,1 [37.5–68.2] points and C BA – 74.1 [50.0–76.0] points, showed that physical activity in the children with PC BA was significantly lower as compared to those with C BA (P < 0.001). The analysis showed no significant difference between the answers of the children with asthma and their parents. No significant difference between the answers of healthy children’s parents and the children themselves was revealed as well (P > 0.05). The cumulative index of QL was dependent on the level of BA control. It was 2.5 [1.4–3.6] points in the children with UC BA, being significantly lower as compared to those with PC BA – 3.9 [2.8–4.9] points, and C BA – 6.2 [5.6–6.8] points (р<0.001); and in the children with PC BA this index was significantly lower as compared to those with C BA (P < 0.01).

Conclusions. Along with traditional methods of assessment of respiratory function and laboratory indices of inflammatory process activity in bronchial asthma, study of physical and mental health, social activity, general well-being and many other parameters of quality of life, as well as the influence of treatment on these parameters should be carried out.

 

References

Gopal, S., & Rai, A. (2016) Parental Stress and Quality of life in Parents of Children with Bronchial Asthma. IJHSR., 6(6), 293–300.

Protsiuk, T. L. (2013) Yakist zhyttia khvorykh na bronkhialnu astmu ditei tа chynnyky, shcho vplyvaiut nа nеi [The quality of life of children with bronchial asthma and the factors affecting on it]. Current issues in pharmacy and medicine: science and practice, 3(13), 66–68. [in Ukrainian].

Wander, A., Bhargava, S., Pooni, P. A., Kakkar, S. & Arora, K. (2017) Quality of life in children with bronchial asthma. J PediatrRes., 4(06), 382–387.

Elshazly, H. M., Mahalawy, I. El., Gabr, H. M., Abd El Naby, S. A. & Elzoghby, E. E. (2015) Quality of life among asthmatic children attending the Outpatient Clinic in Menoufia University Hospital. Menoufia Med J., 28, 442–6.

Al-Gewely, M. S., El-Hosseiny, M., Abou Elezz, N. F., El-Ghoneimy, D. H. & Hassan, A. M. (2013) Health-related quality of life in childhood bronchial asthma. Egypt J. Pediatr. Allergy Immunol., 11(2), 83–93.

Luskin, A. T., Chipps, B. E., Rasouliyan, L., Miller, D. P., Haselkorn, T. & Dorenbaum, A. (2014). Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma. J. Allergy Clin Immunol Pract., 2(5), 544–52.e1-2. doi: 10.1016/j.jaip.2014.02.011.

Heethal, J.P., Khine, K.M., Kenneth, W.C.F., Kum, Y.Z., Irigo, C.I., Nurul, S., & Sanjeev, S. (2014). A Survey on the quality of life in patients with bronchial asthma in an outpatient clinic in Malaysia, Br. J. Med. Med. Res., 4(5), 1187–1194. doi: 10.9734/BJMMR/2014/5985.

Klymenko, V. А., & Каrpushеnkо, Yu. V. (2014) Yakist zhyttia ditei z аlerhichnymy zakhvoriuvanniamy [The quality of life of children with allergic diseases]. Аstmа tа аlеrhіa, 3; 27–29. [in Ukrainian].

Varni, J. W., Burwinkle, T. M., Seid, M., & Skarr, D. (2003). The PedsQL™4.0 as a pediatric population health measure: Feasibility, reliability, and validity. Ambul. Pediatrics, 3(6), 329–341.

Juniper, E. F., Guyatt, G. H., Ferrie, D. H., Ferrie, P. J., Griffith, L. E., & Townsed, M. (1996). Measuring quality of life in the parents of children with asthma. Quality of Life Research, 5(1), 27–34.

Cerović, S., Zivković, Z., Milenković, B., Stojanović, J. J, Bajec, A. O., Vukaŝinović, Z., & Veković, V. (2009). The Serbian version of the pediatric asthma quality of life questionnaire in daily practice. J. Asthma., 46(9), 936–9. doi: 10.3109/02770900903265812.

Zandieh, F., Moin, M. & Movahedi, M. (2006). Assessment of quality of life in Iranian asthmatic children, young adults and their caregivers. Iran J. Allergy Asthma Immunol, 5(2), 79–83. doi: 05.01/ijaai.7983.

Nair, S., Nair, S. & Sundaram, K. R. (2014) A prospective study to assess the quality of life in children with asthma using the pediatric asthma quality of life questionnaire. Indian J. Allergy Asthma Immunol., 28(1), 13–8.

Dean, B. B., Calimlim, B. M., Kindermann, S. L., Khandker, R. K., & Tinkelman, D. (2009) The impact of uncontrolled asthma on absenteeism and health-related quality of life. J. Asthma., 46(9), 861–6. doi: 10.3109/02770900903184237.

Chromá, J., & Slaný, J. (2011) Quality of life of children with bronchial asthma disease. Cas. Lek. Cesk., 150(12), 660–4.

Trzcieniecka-Green, A., Bargiel-Matusiewicz, K., Wilczyńska, A. & Omar, H. A. Quality of Life of Parents of Children with Asthma (2015). International Journal of Child and Adolescent Health, 8(3), 351–355.

Matsunaga, N. Y., Gonçalves de Oliveira Ribeiro, M. A., Bredda Saad, I. A. Morcillo, A. M., Ribeiro, J. D. & Dalbo Contrera Toro, A. (2015) Evaluation of quality of life according to asthma control and asthma severity in children and adolescents. J. Bras. pneumol., 41(6), 206–2011. doi: 10.1590/S1806-37562015000000186

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1.
Herasymova OV, Protsiuk TL, Protsiuk LO, Surkova NM, Kotsur LD, Kuleshov O. The influence of bronchial asthma control level on the quality of life indices. Pathologia [Internet]. 2018Sep.12 [cited 2024Apr.24];(2). Available from: http://pat.zsmu.edu.ua/article/view/141394

Issue

No. 2 (2018)

Section

Original research

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