Influence of industrial atmospheric pollution on the development of pathology of respiratory organs

Authors

  • M. P. Hrebniak Zaporizhzhia State Medical University, Ukraine.,
  • R. A. Fedorchenko Zaporizhzhia State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1237.2019.1.166314

Keywords:

air pollution, respiratory tract diseases, hygienic prenosological diagnostics

Abstract

 

Due to the technogenic load, first of all, the quality of the air basin is disturbed. More than 80 % of diseases depend to some extent on its quality, but in an industrial city, atmospheric pollution determines the priority of pathology of respiratory organs.

The purpose of the work was to study the peculiarities of the development of pathological conditions of the respiratory organs in the population living in conditions of significant atmospheric pollution.

Materials and methods. Industrial emissions into the air basin from enterprises of the metallurgical industry were investigated. The type of violations of ventilation functions (obstruction, restriction, obstruction on the background of restriction) was determined from the “flow – volume” curve of the forced expiration. The incidence was studied according to the statistical materials of hospitals.

Results. The residents of the industrial city have a complex of ecotoxicants, which leads to a dangerous degree of pollution and a very contaminated level. In 53.8 % of the city's residents there are deviations in the ventilation function (by the method of the flow-volume curve analysis) due to the development of obstructive changes in the bronchopulmonary apparatus of the upper respiratory tract. After 49 years of living in such conditions, nearly in all the population prenosological conditions are registered (91.7–93.9 %). With prolonged residence in conditions of contamination, obstruction significantly increases against the background of restriction. The incidence of respiratory diseases in adults is higher with a high level of use of production capacity.

Conclusions. In 53.8 % of the inhabitants of the industrial city, there are deviations in the ventilation function due to the development of obstructive changes in the broncho-pulmonary apparatus of the upper respiratory tract (obstruction combined with a restriction and obstruction).

With age, the proportion of persons with prenosological conditions of respiratory function increases, especially at the age of 30–39 and 40–49 years. A high degree correlation exists between air pollution and population morbidity. Thus, the correlation coefficient between the total city air pollution indexes and respiratory diseases is 0.72 (P < 0.01) in adults and 0.66 (P < 0.05) in children.

The morbidity of the adult population of the megapolis with diseases of the respiratory organs has waved in the last years. The trend of its dynamics was y = 3343.2 – 47.97x, with a coefficient of multiple correlation of 0.78 (P < 0.05). The regularities of long-term chromodynamics of respiratory organs incidence among children is almost the same as at high and at a moderate level of industrial production - dynamics tendency has a look of equation y = 10190.3 – 41.2x and y = 8813.9 – 76.3x with a coefficient of multiple correlation 0.59–0.64 (P < 0.05).

 

References

(2013) Zdorov'e – 2020: Osnovy Evropeyskoj politiki i strategii dlya XXI veka [The foundations of European policy and strategy for the 21st century]. Kopengagen. [in Russian].

(2014) Air quality and health. WHO Information Bulletin № 313. Retrieved from: https://www.who.int/mediacentre/factsheets/fs313/ru/

Petrosian, A. A. (2015) Do pytannia rozrobky metodychnykh pidkhodiv shchodo otsinky yakosti povitria ta zberezhennia hromadskoho zdorovia [Use risk assessment to air quality management and preservation of public health]. Hihiiena naselenykh mists, 66, 47–52. [in Ukrainian].

Turos, O. I., Ananyeva, O. V., & Petrosian, A. A. (2014) Vdoskonalennia pidkhodiv do kilkisnoi otsinky zabrudnennia atmosfernoho povitria vykydamy avtomobilnykh transportnykh zasobiv [Development of an improved approach to quantitative assessment of transport-related air pollution]. Hihiiena naselenykh mists, 63, 22–31. [in Ukrainian].

Tashmetova, G. (2015) Early phenotypes of chronic obstructive pulmonary disease (COPD). European Respiratory Journal, 46(60), 3662. doi: 10.1183/13993003

Pedone, C., Di Marco Berardino, A., Pistelli, R., Forastiere, F., Bellia, V. & Antonelli Incalzi, R. (2016) Can the New Global Lung Initiative Equations better stratify the risk of death in elderly people with chronic obstructive pulmonary disease? Respiration, 92, 16–24. doi: 10.1159/000447246

Tahanovich, А. & Kadushkin, A. (2016) Different changes in plasma concentrations of cytokines and chemokines in patients with COPD associated with smoking and occupational exposures. European Respiratory Journal, 48(60), 394. doi: 10.1183/13993003

Stallberg, B., Janson, C., Larsson, K., Johansson, G., Kostikas, K., Gruenberger, J.-B., et al. (2016). Comorbidities in Swedish COPD and non-COPD patients: ARCTIC study. European Respiratory Journal, 48(60), 870. doi: 10.1183/13993003

Hrebniak, N. P., & Fedorchenko, R. A. (2017) Hihiienichna donozolohichna diahnostyka vplyvu atmosfernykh zabrudnen na orhany dykhannia [Hygienic prenosological diagnosis of the influence of the atmospheric pollution on the respiration organs]. Dovkillia ta zdorovia, 1(81), 15–18. [in Ukrainian].

Gomez-Bastero Fernandez, A., RomeroMuñoz, C., Guerrero Zamora, P., Almadana Pacheco, V., Montemayor Rubio, Teodoro (2016) The questionnaire chronic obstructive pulmonary disease-population screener (COPD-PS) as a screening of the chronic obstructive pulmorary disease (COPD) in a quitting smoke medical practice. European Respiratory Journal, 48(60), 4317. doi: 10.1183/13993003

Shpagina, L., Kotova, O., Shpagin, I., & Gerasimenko, O. (2017) Clinical and inflammatory features of exacerbations of occupational chronic obstructive pulmonary disease. European Respiratory Journal, 50(61), 416. doi: 10.1183/1393003

Sokolov, E. V., & Razzhivina, I. M. (2013) Individual'no-tipologicheskie osobennosti sostoyaniya ventilyacionnoj funkcii legkikh i biomekhanicheskikh faktorov dykhaniya u detej 9–13 let v zavisimosti ot sostoyaniya zdorov'ya [Individual and typological features of the state of ventilation function of lung and biomechanical respiratory factors in children 9–13 years old depending on the state of health]. Novye issledovaniya, 1(34), 79–101. [in Russian].

Stepashkin, K. N., & Demko, I. M. (2012) Vzaimosvyaz' respiratornykh simptomov i dannykh issledovaniya funkcii vneshnego dykhaniya u rabotnikov zheleznodorozhnogo transporta [Correlation of respiratory symptoms and lung function study data in railway workers]. Byulleten' fiziologii i patologii dykhaniya, 45, 38–43. [in Russian].

Kiku, P. F., Izmaylova, O. A., Gorborukova, T. V., & Ananev, V. Yu. (2012) Vliyanie e'kologo-gigienicheskikh faktorov sredy obitaniya na rasprostranenie boleznej organov dykhaniya u naseleniya Primorskogo kraya [The influence of ecological hygiene environmental factors on the distribution of respiratory diseases in population of Primorsky krai]. Gigiena i sanitariya, 91(5), 25–29. [in Russian].

Kajba, S. (2015) The prevalence of co-morbidities and exacerbations in COPD patients in Slovenia. European Respiratory Journal, 46(59), 1122. doi: 10.1183/13993003

Ravi Shekhar Jha (2016) Role of vitamin D supplementation in lung function testing and exercise capacity. European Respiratory Journal, 48(60), 4141. doi: 10.1183/13993003

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How to Cite

1.
Hrebniak MP, Fedorchenko RA. Influence of industrial atmospheric pollution on the development of pathology of respiratory organs. Pathologia [Internet]. 2019May13 [cited 2024Apr.25];(1). Available from: http://pat.zsmu.edu.ua/article/view/166314

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