Peculiarities of transient hyperglycemia in ischemic hemispheric stroke in patients with obesity
DOI:
https://doi.org/10.14739/2310-1237.2012.3.17023Keywords:
abdominal obesity, ischemic stroke, poststroke transient hyperglycemiaAbstract
Ischemic strokes in abdominally obese patients have more severe clinical course. We analyzed glycemia indicators during the first day after hemispheric ischemic strokes in patients with different obesity types and with definite cerebral lesion volumes. Poststroke transient hyperglycemia in abdominally obese patients is more frequent and significantly more intensive in comparison with normal weight patients. Moreover, in abdominally obese patients with non-lacunar hemispheric infarcts larger than 20 cm3 poststroke transient hyperglycemia is significantly more pronounced in comparison with abdominally obese patients who have lacunar strokes or non-lacunar infarcts less than 20 cm3. This phenomenon may be one of the factors that determine more severe stroke clinical course in abdominally obese patients.References
Литвиненко Н.В. Клініко-нейровізуалізаційні характеристики гострого періоду нелакунарних гемісферальних інсультів у осіб з ожирінням / Н.В. Литвиненко, М.Ю. Дельва, І.І. Дельва // Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії. – 2011. – Т. 11, вип. 4 (36), ч. 1. – С. 55–58.
Allport L. Insular cortical ischemia is independently associated with acute stress hyperglycemia / L. Allport, K. Butcher, A. Baird [et al.] // Stroke. – 2004. – V. 35. – P. 1886–1891.
Broderick J.P. Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality / J.P. Broderick, T.G. Brott, J.E. Duldner [et al.] / Stroke. – 1993. – V. 24. – P. 987–993.
Bruno A. Acute blood glucose level and outcome from ischemic stroke. Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators / A. Bruno, J. Biller, H. [et al.] // Neurology. – 1999. – V. 52. – P. 280–284.
Capes S. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview / S. Capes, D. Hunt, K. Malmberg [et al.] // Stroke. – 2001. – V. 32. – P. 2426–2432.
Kagansky N. The Role of Hyperglycemia in Acute Stroke / N. Kagansky, S. Levy, H. Knobler // Arch Neurol. – 2001. – V. 58. – P. 1209–1212.
Mergenthaler P. Pathophysiology of Stroke: Lessons From Animal Models / P. Mergenthaler, U. Dirnagl, A. Meisel // Metabolic Brain Disease. – 2004. – V. 19 (3–4). – P. 151–167.
O’Neill P. Stress hormone and blood glucose response following acute stroke in the elderly / P. O’Neill, I. Davis, K. Fullerton [et al.] // Stroke. – 1991. – V. 22. – P. 842–847.
Parsons M. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study / M. Parsons, P. Barber, P. Desmond [et al.] // Ann Neurol. – 2002. – V. 52. – P. 20–28.
Scott J. Prevalence of admission hyperglycaemia across clinical subtypes of acute stroke / J. Scott, G. Robinson, J. French [et al.] // 1999. – V. – 353. – P. 376–377.
Szczudlik A. Transient hyperglycemia in ischemic stroke patients / A. Szczudlik, A. Slowik, W. Turaj [et al.] // Journal of the Neurological Sciences. – 2001. – V. 189. – P. 105–111.
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus // Diabetes Care. – 2003. – V. 26 (suppl. 1). – P. 5–20.
van Kooten F. Hyperglycemia in the acute phase of stroke is not caused by stress / F. van Kooten, N. Hoogerbrugge, P. Naarding // Stroke. – 1993. – V. 24. – P. 1129–1132.
Williams L. Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke / L. Williams, J. Rotich, R. Qi [et al.] // Neurology. – 2002. – V. 59. – P. 67–71.
World Health Organization: Obesity. Preventing and Managing the Global Epidemic. Report of a WHO Consultation on Obesity, Geneva 3–5 June 1997. Geneva, World Health Organization, 1998.
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