The choice of tactic for surgical treatment of aortic arch hypoplasia with ventricular septal defect in infants

Authors

  • Ya. P. Truba National M. Amosov Institute of Cardiovascular Surgery Affilated to National Academy of Medical Sciences of Ukraine, Kyiv, https://orcid.org/0000-0001-5214-408X
  • V. V. Lazoryshynets National M. Amosov Institute of Cardiovascular Surgery Affilated to National Academy of Medical Sciences of Ukraine, Kyiv, https://orcid.org/0000-0002-1748-561X
  • R. I. Sekelyk Center for Pediatric Cardiology and Cardiac Surgery, Kyiv, Ukraine,
  • I. V. Dziuryi National M. Amosov Institute of Cardiovascular Surgery Affilated to National Academy of Medical Sciences of Ukraine, Kyiv, https://orcid.org/0000-0002-1073-7060
  • O. S. Holovenko National M. Amosov Institute of Cardiovascular Surgery Affilated to National Academy of Medical Sciences of Ukraine, Kyiv, https://orcid.org/0000-0001-6002-3325

DOI:

https://doi.org/10.14739/2310-1237.2020.3.221785

Keywords:

hуpoplasia, aortic arch, ventricular septal defect, infants

Abstract

 

Aim: to determine the optimal tactic for surgical correction of aortic arch hypoplasia and ventricular septal defect (VSD) in infants based on the comparison of immediate and follow-up outcomes of one- and two-stage repair.

Materials and methods. Between 2011 to 2019, 138 patients under the age of one year underwent surgical repair of aortic arch hypoplasia with VSD in the leading Ukrainina cardiosurgical institutions – National M. Amosov Institute of Cardiovascular Surgery Affilated to National Academy of Medical Sciences of Ukraine and Center for Pediatric Cardiology and Cardiac Surgery. Patients were divided into two groups: group I involved 66 (47.8 %) patients who underwent one-stage repai of aortic arch hypoplasia and VSD, group II included 72 (52.2 %) patients with two-stage repair, consisting of aortic arch reconstruction and pulmonary banding at the first stage, and correction of VSD at the second stage.

Results. The total hospital mortality was 3.6 % (n = 5). In group I, hospital mortality was 3.0 % (n = 2), in group II – 4.2 % (n = 3), but this difference is not statistically significant (P > 0.05). Follow-up was from 1 month to 11 years. Mortality rate over follow-up period was 0 %. Aortic arch restenosis developed in 16 (11.6 %) patients: 6 (9.1 %) patients in group I and 10 (13.9 %) patients in group II. There was no statistically significant difference in restenosis development between two groups. Compression of the trachea and left main bronchus developed in two patients of group II (2.8 %). There were no residual VSDs which would need repeated repair.

Conclusions. Both one-stage and two-stage tactic for surgical treatment of aortic arch hypoplasia with VSD in infants is effective and safe showing good immediate and long-term follow-up results. The study indicates that one- stage correction is more acceptable in infants with hypoplasia of segment C or all aortic arch segments. Stage tactic can be used in hypoplasia of segments B and A.

References

Gray, W. H., Wells, W. J., Starnes, V. A., & Kumar, S. R. (2018). Arch Augmentation via Median Sternotomy for Coarctation of Aorta With Proximal Arch Hypoplasia. The Annals of thoracic surgery, 106(4), 1214-1219. https://doi.org/10.1016/j.athoracsur.2018.04.025

Plunkett, M. D., Harvey, B. A., Kochilas, L. K., Menk, J. S., & St Louis, J. D. (2014). Management of an associated ventricular septal defect at the time of coarctation repair. The Annals of thoracic surgery, 98(4), 1412-1418. https://doi.org/10.1016/j.athoracsur.2014.05.076

Callahan, C., Saudek, D., Shillingford, A., Creighton, S., Hill, G., Johnson, W., Tweddell, J. S., Mitchell, M. E., & Woods, R. K. (2017). Single-Stage Repair of Coarctation of the Aorta and Ventricular Septal Defect: A Comparison of Surgical Strategies and Resource Utilization. World journal for pediatric & congenital heart surgery, 8(5), 559-563. https://doi.org/10.1177/2150135117727256

Dutta, N., Ghosh, R., Awasthy, N., Girotra, S., Radhakrishnan, S., Shrivastava, S., Iyer, P. U., & Iyer, K. S. (2016). Off-pump midline repair of coarctation of aorta when associated with intracardiac defects: an alternate approach for single-stage correction. European journal of cardio-thoracic surgery, 50(6), 1089-1095. https://doi.org/10.1093/ejcts/ezw260

Wu, Y., Li, J., Wu, C., Zhu, J., He, L., Feng, C., Yang, Y., & Jin, X. (2020). Diagnosis and Surgical Repair for Coarctation of the Aorta with Intracardiac Defects: A Single Center Experience Based on 93 Infants. Frontiers in pediatrics, 8, 49. https://doi.org/10.3389/fped.2020.00049

Kornilov, I. A., Sinelnikov, Y. S., Soinov, I. A., Ponomarev, D. N., Kshanovskaya, M. S., Krivoshapkina, A. A., Gorbatykh, A. V., & Omelchenko, A. Y. (2015). Outcomes after aortic arch reconstruction for infants: deep hypothermic circulatory arrest versus moderate hypothermia with selective antegrade cerebral perfusion. European journal of cardio-thoracic surgery, 48(3), e45-e50. https://doi.org/10.1093/ejcts/ezv235

Axelrod, D. M., Chock, V. Y., & Reddy, V. M. (2016). Management of the Preterm Infant with Congenital Heart Disease. Clinics in perinatology, 43(1), 157-171. https://doi.org/10.1016/j.clp.2015.11.011

Gaynor, J. W. (2003). Management strategies for infants with coarctation and an associated ventricular septal defect. The Journal of Thoracic and Cardiovascular Surgery, 125(3), S87-S89. https://doi.org/10.1067/mtc.2003.238

De León, L. E., & McKenzie, E. D. (2017). Aortic Arch Advancement and Ascending Sliding Arch Aortoplasty for Repair of Complex Primary and Recurrent Aortic Arch Obstruction. Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual, 20, 63-66. https://doi.org/10.1053/j.pcsu.2016.09.007

How to Cite

1.
Truba YP, Lazoryshynets VV, Sekelyk RI, Dziuryi IV, Holovenko OS. The choice of tactic for surgical treatment of aortic arch hypoplasia with ventricular septal defect in infants. Pathologia [Internet]. 2020Dec.29 [cited 2024Nov.23];(3). Available from: http://pat.zsmu.edu.ua/article/view/221785

Issue

Section

Original research