Features of myocardial deformation in patients with ischemic heart disease with moderate dilatation of cavity of the left ventricle complicated by the myocardial infarction

Authors

  • A. V. Molodan
  • V. A. Ivashchuk

DOI:

https://doi.org/10.14739/2310-1237.2014.1.25250

Keywords:

myocardial ischemia, left ventricle, ultrasonography

Abstract

Aims. To explore the features of the myocardial deformation in patients with IHD.

Research objective: to study features of function of myocardium of the left ventricle in patients with IHD with the moderate dilatation of the left ventricle complicated by the myocardial infarction.

Methods and results.135 patients were included into the study. 60 of them had IHD with moderate left ventricle dilatation not complicated by myocardial infarction. 40 patients had IHD with myocardial infarction in anamnesis, 35 were healthy (comparison group). Left ventricle images were analyzed in concordance with 18-segmental model in grey scale as well as in the MSI and TDI regimen.

Primary levels of the myocardial deformation in patients with myocardium infarction were commonly less than in patients without infarction. In that group we got lowest parameters of the myocardial deformation (strain) (8%-11%) in the lateral middle, lower basal and middle, posterior middle and anterior middle segments (42%). That fact can be explained by the highest level of the coronary circulation insufficiency and the presence of the postinfarction myocardial scars. Indices of the deformation close to normal (>13-20%) were detected in the 15% of the left ventricle segments.

In 67% of the analyzed segments we detected decrease of the LV deformation (strain) by 6-25% from the normal values. Vector analysis of the longitudinal systolic and diastolic LV deformation in patients with IHD with moderate LV dilatation and myocardial infarction was done. Results had no significant difference in comparison with control in all septal segments both in systole and in diastole. Change of the diastolic function in the patients with IHD with moderate LV dilatation and MI was detected as decrease of the speed of the early diastolic filling, increase of the time of the isovolumetric relaxation and other parameters. A difference between viable and nonviable tissue in patients with the expressed dysfunction of the left ventricle has great clinical value and it must be appraised in every case. Only at the revealing of viable myocardium measures for its revascularization become justified or in the absence of the conditions for stenting and CABG, СSWT, if myocardium is nonviable conservative therapy should be done.

Conclusion. Vector analysis of the longitudinal systolic and diastolic left ventricle deformity in patients with IHD with moderate left ventricle dilatation as compared with control was made. Significant differences in all segments of the ventricular septum were found both in systole and diastole. 

References

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How to Cite

1.
Molodan AV, Ivashchuk VA. Features of myocardial deformation in patients with ischemic heart disease with moderate dilatation of cavity of the left ventricle complicated by the myocardial infarction. Pathologia [Internet]. 2014Jun.18 [cited 2024Mar.2];(1). Available from: http://pat.zsmu.edu.ua/article/view/25250

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Original research