Senile asthenia as a predictor of the severity of the perioperative period in elderly and senile patients

Authors

DOI:

https://doi.org/10.14739/2310-1237.2022.3.260273

Keywords:

Edmonton Frail, senile asthenia, acute cholecystitis

Abstract

The aim. To evaluate the effectiveness of the diagnosis of senile asthenia using the Edmonton Frail scale in emergency abdominal surgery and to determine its impact on the severity of the perioperative period.

Materials and methods. The study included 81 patients with acute cholecystitis on the background of gallstone disease, who were assessed for senile asthenia using the Edmonton Frail scale. For the reliability of the obtained results, only patients who were urgently hospitalized to the surgical department with gynecology beds of the emergency hospital with clinical symptoms of acute cholecystitis were included. All patients received treatment in only one department and according to the standards and clinical protocols of this clinic. Based on the Edmonton Frail score, all patients were divided into two groups. The comparison group included 50 (61.7 %) patients who did not have senile asthenia. The main group included 31 (38.3 %) patients diagnosed with senile asthenia.

Results. Surgical treatment in both groups was carried out on an urgent basis using total intravenous anesthesia with artificial lung ventilation. According to the type of surgical intervention in both groups, preference was given to minimally invasive methods. Laparoscopic cholecystectomy in the comparison group was performed in 49 (98.0 %) patients, and only one patient (2.0 %) was converted and operation continued from the mini-access. In the main group, all surgical interventions were performed by the laparoscopic method, U = 759.50, P = 0.8841. Analyzing the results of the duration parameters and the need for prolonged mechanical ventilation, it can be seen that it progressively increases in patients with asthenia: in the comparison group 61.50 (48.00; 75.00) minutes, and in the main 93.84 (60.00; 80.00), U = 513.50, P = 0.0112. Also, we noted that in patients with senile asthenia, the number of postoperative complications increases: in the comparison group, there were only 2 (4.0 %) postoperative complications, while in the main group – 7 (22.6 %), U = 556.00, Р = 0.0337.

Summarizing the results, it can be seen that due to increase of the frequency of postoperative complications and increase of the need for prolonged artificial ventilation of the lungs, the length of hospital stay of patients with senile asthenia increased: in the comparison group it was 7.9 ± 2.2 days, and in the main group 9.7 ± 3.2 days, U = 530.50, P = 0.0177.

Conclusions. In our opinion, the Edmonton Frail scale is effective in diagnosing the severity of senile asthenia in elderly and senile patients in emergency abdominal surgery due to its simplicity and speed of use. The overall severity of the condition, heart failure in patients with senile asthenia lead to increase in the duration of surgery and the total duration of artificial lung ventilation: in the comparison group 39.52 (30.00; 45.00) minutes, while in the main group 49.19 (35.00; 50.00) minutes, U = 482.50, P = 0.0046. The duration of mechanical ventilation also differed significantly, in the comparison group 61.50 (48.00; 75.00) minutes, and in the main – 93.84 (60.00; 80.00), U = 513.50, P = 0.0112. The severity of senile asthenia negatively affects the course of the perioperative period, the frequency of postoperative complications increases: 2 (4.0 %) patients in the comparison group, while in the main group of 7 (22.6 %) patients, U = 556.00, P = 0.0337 and, as a consequence, the duration of inpatient treatment increases: in the comparison group it was 7.9 ± 2.2 days, in the main – 9.7 ± 3.2, U = 530.50, P = 0.0177. Modification of the approaches to preoperative preparation and postoperative management of elderly and senile patients diagnosed with senile asthenia will reduce the frequency of postoperative complications and reduce the length of hospital stay.

Author Biographies

M. B. Danyliuk, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education

S. M. Zavhorodnii, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Professor of the Department of General Surgery and Postgraduate Surgical Education

A. I. Rylov, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education

M. A. Kubrak, Zaporizhzhia State Medical University, Ukraine

PhD, Аssistant of the Department of General Surgery and Postgraduate Surgical Education

I. V. Pertsov, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of General Surgery and Postgraduate Surgical Education

References

Gale, C. R., Cooper, C., & Sayer, A. A. (2015). Prevalence of frailty and disability: findings from the English Longitudinal Study of Ageing. Age and ageing, 44(1), 162-165. https://doi.org/10.1093/ageing/afu148

Guidet, B., de Lange, D. W., Boumendil, A., Leaver, S., Watson, X., Boulanger, C., Szczeklik, W., Artigas, A., Morandi, A., Andersen, F., Zafeiridis, T., Jung, C., Moreno, R., Walther, S., Oeyen, S., Schefold, J. C., Cecconi, M., Marsh, B., Joannidis, M., Nalapko, Y., … VIP2 study group (2020). The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive care medicine, 46(1), 57-69. https://doi.org/10.1007/s00134-019-05853-1

Nahorna, A. M., Basanets, А. V., Kononova, I. G., Medvedovska, N. V., & Gvozdetskiy, V. A. (2021). Stan zdorovia naselennia pratsezdatnoho viku ta efektyvnist funktsionuvannia systemy okhorony zdorovia Ukrainy [The state of health of the working age population and the effectiveness of the health care system in Ukraine]. Ukraina. Zdorovia natsii, (1), 5-22. [in Ukrainian].

Chepelevska, L. A. (2018). Tendentsii medyko-demohrafichnykh pokaznykiv Ukrainy u XXI stolitti [Trends in medical and demographic indicators of Ukraine in the XXI century]. Ukraina. Zdorovia natsii, (1), 48-52. [in Ukrainian].

Wæhler, I. S., Saltvedt, I., Lydersen, S., Fure, B., Askim, T., Einstad, M. S., & Thingstad, P. (2021). Association between in-hospital frailty and health-related quality of life after stroke: the Nor-COAST study. BMC neurology, 21(1), 100. https://doi.org/10.1186/s12883-021-02128-5

Cardoso, A. L., Fernandes, A., Aguilar-Pimentel, J. A., de Angelis, M. H., Guedes, J. R., Brito, M. A., Ortolano, S., Pani, G., Athanasopoulou, S., Gonos, E. S., Schosserer, M., Grillari, J., Peterson, P., Tuna, B. G., Dogan, S., Meyer, A., van Os, R., & Trendelenburg, A. U. (2018). Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. Ageing research reviews, 47, 214-277. https://doi.org/10.1016/j.arr.2018.07.004

Faller, J. W., Pereira, D. D. N., de Souza, S., Nampo, F. K., Orlandi, F. S., & Matumoto, S. (2019). Instruments for the detection of frailty syndrome in older adults: A systematic review. PloS one, 14(4), e0216166. https://doi.org/10.1371/journal.pone.0216166

Rolfson, D. B., Majumdar, S. R., Tsuyuki, R. T., Tahir, A., & Rockwood, K. (2006). Validity and reliability of the Edmonton Frail Scale. Age and ageing, 35(5), 526-529. https://doi.org/10.1093/ageing/afl041

Ijaz, N., Buta, B., Xue, Q. L., Mohess, D. T., Bushan, A., Tran, H., Batchelor, W., deFilippi, C. R., Walston, J. D., Bandeen-Roche, K., Forman, D. E., Resar, J. R., O'Connor, C. M., Gerstenblith, G., & Damluji, A. A. (2022). Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 79(5), 482-503. https://doi.org/10.1016/j.jacc.2021.11.029

Published

2023-01-27

How to Cite

1.
Danyliuk MB, Zavhorodnii SM, Rylov AI, Kubrak MA, Pertsov IV. Senile asthenia as a predictor of the severity of the perioperative period in elderly and senile patients. Pathologia [Internet]. 2023Jan.27 [cited 2024Mar.1];19(3):189-94. Available from: http://pat.zsmu.edu.ua/article/view/260273

Issue

Section

Original research