Pathomorphological features of the structure of the uterus of fetuses from mothers with pregnancy complicated by pre-eclampsia of varying degrees of severity
DOI:
https://doi.org/10.14739/2310-1237.2014.2.28545Keywords:
Pregnancy, Fetus, Uterus, PreeclampsiaAbstract
Aim. In order to determine the effect of preeclampsia (PE) of the mother on the structural pecularities of uterus of fetuses the structure of the uterus of 41 antenatally dead fetuses was studied using organometric, histologic, histochemical, morphometric and statistical methods.
Methods and results. It has been established that the maximum decrease of indices of mass and length of the uterus is in fetuses of mothers with medium degree of PE and severe PE, the minimum - in fetuses of mothers with mild PE. Unidirectional changes were found in the calculation of indicators of the wall thickness of the uterus and its structural components. Histological structure of the uterus of fetuses from mothers with PE is characterized by proliferation of the glandular epithelium; growth of coarse fibrous connective tissue in the mucous membranes and muscle layers; dystrophic and necrotic changes in the vascular endothelium.
Conclusion. Identified features can manifest themselves in reproductive dysfunction in the future ontogenesis.
References
Ryshkevych, Yu., Fіlova, A., Hmelevska, K., et al. (2010) Ekstrahenitalna patolohiia u vahitnykh riznokho viku [Extragenital pathology in pregnant women of all ages]. Proceedings of the International medical Congress, (162). Ternopil [in Ukrainian].
Тikhomirov, A. L. & Lubnin, D. M. (2009) Prakticheskaya ginekologiya: rukovodstvo dlya vrachej [Practical Gynecology: A Guide for Physicians]. Moscow: MIA [in Russian].
Boreichuk, O. (2010) Klіnіko-morfologіchnyi mill novonarodzhenikh od materіv z vagіtnіstiu, uskladnenoiu hestozom [Clinical and morphological status of newborns from mothers with pregnancy complicated by preeclampsia]. Proceedings of the International medical Congress, (147).Ternopil [in Ukrainian].
Verkhoshanova, O. G., Novokhackaya, S. V. & Udovikova, N. A. (2013) Klinicheskie osobennosti pervichnoj oligomenorei u devochek-podrostkov [Clinical features of primary oligomenorrhea adolescent girls]. Endokrynna patolokhiia u vikovomu aspekti. Proceedings of the International Scientific and Praktscal Conference, (18–19). Kharkiv [in Ukrainian].
Sidorova, I. S., Bilyavskaya, O. S., Nikitina, N. A., et al. (2008) Ocenka stepeni tyazhesti gestoza (po dannym literatury) [Assessment of the severity of preeclampsia (according to the literature)]. Akusherstvo i hinekolohiya, (3), 40–43. [in Russian].
Subbotin, M. Ya., Laguchev, S. S., & Oganesyan, T. G. (1954) Gistologicheskaya tekhnika [Histology Equipment]. Moscow: Medgiz. [in Russian].
Atramentova, L. A. & Utevskaya, O. M. (2008) Statisticheskie metody v biologii [Statistical methods in biology]. Gorlivka. [in Ukrainian].
Dynnik, V. A. (2013) Sutochnyj ritm sekrecii gonadotropnykh gormonov i prolaktina u devochek-podrostkov s anomal'nymi matochnymi krovotecheniyami [Daily rhythm of secretion of gonadotropin-releasing hormone and prolactin levels in adolescent girls with abnormal uterine bleeding]. Endokrynna patolokhiia u vikovomu aspekti. Proceedings of the International Scientific and Praktscal Conference, (27–29). Kharkiv [in Ukrainian].
Kravchun, N. A. & Chernyavskaya, I. V. (2008) Sovremennyj vzglyad na sochetannuyu autoimmunnuyu e`ndokrinnuyu patologiyu [Modern view of the conjoint autoimmune endocrine pathology]. Problemy endokrynnoi patolohii, (1), 84–89. [in Ukrainian].
Rosas, M., Lomelí, S., & Mendoza-González, S. (2008). Hypertension and pregnancy. Arch. Cardiol., (78), 104–108.
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