Ratio of the blood flow in liver and splenic arteries in patients with various forms of portal hypertension
DOI:
https://doi.org/10.14739/2310-1237.2015.3.56112Keywords:
Portal Hypertension, Doppler Ultrasonography, Liver CirrhosisAbstract
Each type of portal hypertension has clinical and diagnostic peculiarities, which determines the choice of therapeutic approach and subsequently an outcome.
Aim. In order to evaluate the arterial blood flow of the liver, which can be ambiguous in the syndrome of portal hypertension, in 85 patients with liver cirrhosis, pre-hepatic and post-hepatic forms of portal hypertension the ratio of arterial blood flow in the hepatic and splenic arteries was studied.
Methods and results. To assess the hepatic arterial blood flow, we have introduced a new index – hepato-splenic arterial index, which is determined as the ratio of the flow rates in proper hepatic and splenic arteries. In cirrhosis of the liver, blood flow in the hepatic artery was increased in relation to spleen. With pre-hepatic and post-hepatic forms of portal hypertension which decrease and increase amount of arterial blood in total liver blood flow, respectively, the ratio of arterial blood flow in the hepatic and splenic arteries is unchanged.
Conclusion. This suggests that the hepato-splenic arterial index can serve as a differential criterion for determination of causes of portal hypertension syndrome.
References
Afukova, O. A. & Yudin, A. L. (2005) Luchevaya diagnostika cyroza pecheni [Imaging in Liver Cirrhosis (Review article)]. Medicinskaya vizualizaciya, 32–44. [in Russian].
Garbuzenko, D. V. (2012) Metody prognozirovaniya riska i monitoring e′ffektivnosti terapii krovotechenij iz varikozno-rasshyrenykh ven pishchevoda u bol′nykh cyrrozom pecheni [Methods of risk prediction and monitoring the effectiveness of therapy of bleeding from varicose veins of the esophagus in patients with liver cirrhosis]ю Rossijskij zhurnal gastroe′ntjerologii, gepatologii, koloproktologii, 22(2), 36–44. [in Russian].
Alan, P. A. (Ed). (2001). Klinichna dopplerivska ultrasonohrafiia [Clinical Doppler ultrasonography]. Lviv: Medytsyna svitu. [in Ukrainian].
Medvedev, V. Ye., & Kalymon, O. R. (2006) Ultrazvukova dopplerohrafiia pry tsyrozi pechinky [Ultrasound dopplerography in liver cirrhosis]. Promeneva diahnostyka, promeneva terapiia, 2, 22–30. [in Ukrainian].
Nichitajlo, M. E., Ganzhij, V. V., Tugushev, A. S., & Andrienko, S. A. (2014) Ocenka pechonochnogo krovotoka pri ciroze pecheni [Evaluation of hepatic blood flow in liver cirrhosis]. Klinicha khirurhiia, 3, 22–30. [in Ukrainian].
Rykhtik, P. I. (2007) Kompleksnaya ul′trazvukovaya ocenka regionarnogo krovotoka pri portalnoj gipertenzii i prognosticheskoe znachenie dlya portosistemnogo shuntirovaniya (Avtoref. dis…kand. med. nauk). [Complex ultrasonic estimation of regional blood flow in portal hypertension and prognostic value for portosystemic shunting]. (Extended abstract of candidate’s thesis). Nizhnij Novgorod [in Russian].
Tuhushev, A. S., Klymenko, V. N., Tumanskaia, N. V., & Polyshchuk, L. M. (patentee) (2008). Patent na korysnu model №29527 «Sposib diahnostyky tsyrozu pechinky» [Method of diagnosing liver cirrhosis]. Biuleten, 1. [in Ukrainian].
Tuпushev, A. S., Tumanskaya, N. V., & Materuhin, A. N. (2009) Osobennosti arterial′nogo krovotoka pri cyroze pecheni [Especially arterial blood flow in liver cirrhosis]. Zaporozhskij medicinskij zhurnal, 2(2), 35–37. [in Ukrainian].
Sherlok, Sh., Duli. Dzh. (2002). Zabolevaniya pecheni i zhelchnykh putej: prakticheskoe rukovodstvo [Diseases of liver and bilious ways: practical guidance]. Moscow: GEOTAR-MED. [in Russian].
Shipov, O. Yu. (2002). Diagnostika portal′noj gipertenzii pri ul′trazvukovoj angiografii pecheni (Avtoref. dis…kand. med. nauk). [Diagnosis of portal hypertension in ultrasonic angiography of the liver] (Extended abstract of candidate’s thesis). Moscow. [in Russian].
Baik, S. K. (2010). Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension: a review. Liver International, 30(10), 1403–1413. doi: 10.1111/j.1478-3231.2010.02326.x.
Kim, M. Y., Jeong, W. K., & Baik, S. K. (2014). Invasive and non-invasive diagnosis of cirrhosis and portal hypertension. World J Gastroenterol, 20(15), 4300–4315. doi: 10.3748/wjg.v20.i15.4300.
Kukla, M. (2013). Angiogenesis: a phenomenon which aggravates chronic liver disease progression. Hepatology International, 7(1), 4–12. doi: 10.1007/s12072-012-9391-2.
Stutchfield, B. M., & Forbes, S. J. (2013). Liver sinusoidal endothelial cells in disease – And for therapy? J Hepatology, 58(1), 178–180. doi:10.1016/j.jhep.2012.07.046.
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