Differentiated treatment of patients with acne and concomitant candida infection

Authors

  • Yaakubi Randa Zaporizhzhia State Medical University,

DOI:

https://doi.org/10.14739/2310-1237.2016.3.87501

Keywords:

Candidiasis, Acne Vulgaris, Calcium, Hormones, Microbial Consartia, Therapeutics

Abstract

There are a lot of works, which are devoted to the study of acne, but these data are often contradictory on the issue of interrelationship and interdependence of clinical manifestations, course and some factors in the pathogenesis of acne and candida infection.

Aim of the research was to study the effect of the recommended differentiated therapy on the pathogenetic disorders in patients with acne and concomitant Candida infection.

Methods and results. 120 patients with acne were examined. In 100 of them concomitant skin malasseziosis was set in the form of pityriasis rosea, kerosis, comedones, folliculitis, seborrhea, multicolored zoster, with some features, as well as candidiasis. Methods of the research – bacterioscopic, bacteriological, study of skin oiliness and moisture, skin pH, the level of Ca ++, parathyroid hormone and calcitonin. In patients with acne significant shifts in the composition of water-lipid mantle, increased oiliness and decreased moisture of skin, pH changes with a shift to the alkaline side were revealed, the most pronounced – in acne patients with Candida infection. The content of Ca ++ in the organism, as well as parathyroid hormone and calcitonin was increased and also the most indicative it was in patients with acne and concomitant Candida infection. After the comparative analysis on the basis of different levels of clinical and laboratory violations two clinical-therapeutic groups were distinguished, in accordance with that the differentiated therapy offered by us was conducted. Increased oiliness and Рh of skin, decline of moisture before the treatment, especially in patients with III and IV stages of acne, complicated by Candida infection, were normalized after treatment, unlike in patients treated traditionally.

Conclusion. After treatment intensity of microbal colonization and also microbal associations of skin was diminished, the level of Ca++, parathyroid hormone and calcitonin went down.

References

Adaskevich, V. N. (2005). Akne vul'garnye i rozovye [Acne vulgaris and rosacea]. Moscow: Medkniga; Nizhny Novgorod: NGMA. [in Russian].

Akhtyamov, S. N. (2003) Podkhody k terapii akne v praktike dermatokosmetologa [The therapy of acne in practice of dermatocosmetology]. Vestnik poslediplomnogo medicinskogo obrazovaniya, 3–4, 71–73. [in Russian].

Akhtyamov, S. N., & Safarova, G. G. (2003) Vul'garnyye ugri: voprosy e´tiologii i patogeneza [Acne vulgaris: the questions of ethiology and pathogenesis]. Vestnik poslediplomnogo medicinskogo obrazovaniya, 3–4, 86. [in Russian].

Barinova, A. N. (2003) Vul'garnyye ugri: patogenez, klinika i lecheniye. Sovremennoye sostoyaniye problemy [Acne vulgaris: pathogenesis, clinics and therapy. Modern state of problem]. Rossijskij semejnyj vrach, 7(3), 30–42. [in Russian].

Dobrokhotova, Y. E´., Korsunskaya, I. M., Ragimova, Z. E´, Dzhobava, E´. M., Goryachkina, M. V., & Badzhelan, B. (2008) Giperandrogeniya i akne v praktike ginekologa i dermatologa: voprosy diagnostiki i terapii [Gyperandrogenia and acne in practice of gynaecologist and dermatologist : questions of diagnostics and therapy]. Rossijskij medicinskij zhurnal, 16(1), 54–56. [in Russian].

Zabnenkova, O. V. (2003) Sovremennyye aspekty e´tiopatogeneza acne valgaris. Osnovnaya terapiya dannogo zabolevaniya [Modern aspects of ethiology and pathogenesis of acne valgaris. Basic therapy of this disease]. E´ksperimental´naya i klinicheskaya dermatokosmetologiya, 1, 53–61. [in Russian].

Potekaev, N. N., Goryachkina, M., & Belousova, T. A. (2008) Akne (ugrevaya bolezn'): sovremennyj vzglyad na problemu [Acne: modern look to the problem]. Consilium medicum. Dermatologija, 1, 12–16. [in Russian].

Suvorova, K. N., & Kotova, N. V. (1999) Yunosheskiye ugri – klinika, patogenez, lecheniye [Acne vulgaris – clinic, pathogenesis, therapy]. Rossijskij zhurnal kozhnyh i venericheskikh boleznej, 3, 67–72. [in Russian].

How to Cite

1.
Randa Y. Differentiated treatment of patients with acne and concomitant candida infection. Pathologia [Internet]. 2016Dec.23 [cited 2024Dec.25];(3). Available from: http://pat.zsmu.edu.ua/article/view/87501

Issue

Section

Original research