A clinical case of diffuse odontogenic facial phlegmon
DOI:
https://doi.org/10.14739/2310-1237.2025.1.323480Keywords:
clinical study, inflammatory disease, complex treatment, inflammation, analysisAbstract
The aim of the work is to describe and discuss an unusual clinical case of diffuse facial phlegmon in order to increase the awareness and competence of clinicians who may encounter similar cases.
Materials and methods. For the study, a clinical analysis of episodes of inpatient treatment of patients with odontogenic phlegmon (cellulitis) of one or more cellular spaces of the maxillofacial region was conducted. All clinical cases underwent a thorough clinical analysis, and a treatment plan was drawn up. In this article, we present a description of a case, in our opinion, the most difficult during the studied period, with a hospital treatment period of 25 days.
Results. Patient M., 56 years old, was hospitalized in the department of maxillofacial surgery and otolaryngology of the Municipal Non-Commercial Enterprise “City Hospital of Emergency and Urgent Medical Care” of the Zaporizhzhia City Council. The diagnosis was “Odontogenic diffuse phlegmon of the right half of the face. Exacerbation of chronic periodontitis 4.6”.
The course of the disease was slow. The severity of the disease was due to the prevalence of the purulent process and the presence of concomitant chronic pathologies in the patient, such as diabetes mellitus, nephropathy of mixed genesis. In the hospital, the patient suffered hospital pneumonia. Several surgical interventions were performed to drain purulent foci, necrectomy, and sanitation of the oral cavity. The patient’s treatment was carried out comprehensively with the involvement of related specialists. At the time of recovery, after 25 days of inpatient treatment, the patient had significant local negative consequences of the disease and surgical intervention: facial nerve paresis, cicatricial facial deformities, muscle contracture, atrophy of the fatty tissue of half of the face.
Conclusions. The given case shows that odontogenic phlegmons of the face retain the position of severe and dangerous purulent diseases, which can have (despite the presence of powerful antibiotics and surgical options) a severe and diffuse course with a long hospital treatment period, and lead to functional and aesthetic disorders.
References
Lichman VO, Avetikov DS, Lokes KP, Skikevich MG, Bondarenko VV, Prykhidko RA. [The application of placenta cryoextract in complex treatment of patients with phlegmons of maxillofacial localization]. Ukrainskyi stomatolohichnyi almanakh. 2020;(2):58-62. Ukrainian. doi: https://doi.org/10.31718/2409-0255.2.2020.09
Kiptiliy AV. [Comparative characteristics of treatment methods for patients with odontogenic phlegmons]. Ukrainskyi stomatolohichnyi almanakh. 2023;(1):21-5. Ukrainian. doi: https://doi.org/10.31718/2409-0255.1.2023.04
Actor JK, Nguyen TKT, Wasik-Smietana A, Kruzel ML. Modulation of TDM-induced granuloma pathology by human lactoferrin: a persistent effect in mice. Biometals. J. Dairy Sci. 2022;106:7329-35. doi: https://doi.org/10.1007/s10534-022-00434-0
Pirvulescu RA, Vasile VA, Romanitan MO, Zemba M, Ciulei OC, Geamanu A, et al. Odontogenic Orbital Cellulitis at the Crossroads of Surgeries: Multidisciplinary Management and Review. Diagnostics. 2024;14(13):1391. doi: https://doi.org/10.3390/diagnostics14131391
Burgos-Larraín LF, Vázquez-Portela Á, Cobo-Vázquez CM, Sáez-Alcaide LM, Sánchez-Labrador L, Meniz-García C. Brain complications from odontogenic infections: A systematic review. J Stomatol Oral Maxillofac Surg. 2022;123(6):e794-e800. doi: https://doi.org/10.1016/j.jormas.2022.07.018
Jevon P, Abdelrahman A, Pigadas N. Management of odontogenic infections and sepsis: an update. Br Dent J. 2020;229(6):363-70. doi: https://doi.org/10.1038/s41415-020-2114-5
Evsen EA, Candan M. Serious Complications and Treatment Strategies Associated with Odontogenic Infections. Eurasian J Med. 2023;55(1):142-9. doi: https://doi.org/10.5152/eurasianjmed.2023.23378
Caranfa JT, Yoon MK. Septic cavernous sinus thrombosis: A review. Surv Ophthalmol. 2021;66(6):1021-30. doi: https://doi.org/10.1016/j.survophthal.2021.03.009
World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191-4. doi: https://doi.org/10.1001/jama.2013.281053
Thuy DB, Campbell J, Thuy CT, Hoang NV, Voong Vinh P, Nguyen TN, et al. Colonization with Staphylococcus aureus and Klebsiella pneumoniae causes infections in a Vietnamese intensive care unit. Microb Genom. 2021;7(2):000514. doi: https://doi.org/10.1099/mgen.0.000514
Gerasymenko N, Digtiar N. [A clinical case of hospital-acquired pneumonia caused by klebsiella pneumonia, due to contact with a family member]. Problemy ekolohii ta medytsyny. 2021;25(5-6):24-7. Ukrainian. doi: https://doi.org/10.31718/mep.2021.25.5-6.06
Grillo R, Borba AM, Brozoski M, Moreira SB, da Silva YS, da Graça Naclério-Homem M. Evolution of the treatment of severe odontogenic infections over 50 years: A comprehensive review. J Taibah Univ Med Sci. 2022;18(2):225-33. https://doi.org/10.1016/j.jtumed.2022.08.008
González-Moles MÁ, Ramos-García P. State of Evidence on Oral Health Problems in Diabetic Patients: A Critical Review of the Literature. J Clin Med. 2021;10(22):5383. doi: https://doi.org/10.3390/jcm10225383
Negrini TC, Carlos IZ, Duque C, Caiaffa KS, Arthur RA. Interplay Among the Oral Microbiome, Oral Cavity Conditions, the Host Immune Response, Diabetes Mellitus, and Its Associated-Risk Factors-An Overview. Front Oral Health. 2021;2:697428. doi: https://doi.org/10.3389/froh.2021.697428
Obeagu EI, Igwe MC, Obeagu GU. Oxidative stress's impact on red blood cells: Unveiling implications for health and disease. Medicine (Baltimore). 2024;103(9):e37360. doi: https://doi.org/10.1097/MD.0000000000037360
Hammad Y, Neal TW, Schlieve T. Admission C-reactive protein, WBC count, glucose, and body temperature in severe odontogenic infections: a retrospective study using severity scores. Oral Surg Oral Med Oral Pathol Oral Radiol. 2022;133(6):639-42. doi: https://doi.org/10.1016/j.oooo.2021.11.002
Neal TW, Schlieve T. Complications of Severe Odontogenic Infections: A Review. Biology. 2022;11(12):1784. doi: https://doi.org/10.3390/biology11121784
Steblovskyi DV, Kopchak AV, Lokes KP, Bilokon SO, Voloshyna LI, Popovych IY. Prevalence of inflammatory diseases of the nose among patients with odontogenic purilent-inflammatory diseases of maxillo-facial location. Bulletin of problems in biology and medicine. 2024;(1):518-22. doi: https://doi.org/10.29254/2077-4214-2024-1-172-518-522
Gabriel A, Chan V, Caldarella M, Wayne T, O'Rorke E. Cellulite: Current Understanding and Treatment. Aesthet Surg J Open Forum. 2023;5:ojad050. doi: https://doi.org/10.1093/asjof/ojad050
Lin J, Jimenez CA. Acute mediastinitis, mediastinal granuloma, and chronic fibrosing mediastinitis: A review. Semin Diagn Pathol. 2022;39(2):113-9. doi: https://doi.org/10.1053/j.semdp.2021.06.008
Słotwińska-Pawlaczyk A, Orzechowska-Wylęgała B, Latusek K, Roszkowska AM. Analysis of the Clinical Status and Treatment of Facial Cellulitis of Odontogenic Origin in Pediatric Patients. Int J Environ Res Public Health. 2023;20(6):4874. doi: https://doi.org/10.3390/ijerph20064874
Jabłońska-Trypuć A, Makuła M, Włodarczyk-Makuła M, Wołejko E, Wydro U, Serra-Majem L, Wiater J. Inanimate Surfaces as a Source of Hospital Infections Caused by Fungi, Bacteria and Viruses with Particular Emphasis on SARS-CoV-2. International Int J Environ Res Public Health. 2022;19(13):8121. doi: https://doi.org/10.3390/ijerph19138121
Pham Dang N, Delbet-Dupas C, Mulliez A, Devoize L, Dallel R, Barthélémy I. Five Predictors Affecting the Prognosis of Patients with Severe Odontogenic Infections. Int J Environ Res Public Health. 2020;17(23):8917. doi: https://doi.org/10.3390/ijerph17238917
Downloads
Additional Files
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 A. S. Varzhapetian, O. O. Kokar

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.