Клінічні особливості міксоми лівого передсердя в поєднанні з активним туберкульозом легень

M. Yu. Kolesnyk; O. V. Nikityuk; O. V. Komarova-Laz’ko; S. N. Gulevskij; A. M. Kiosov

doi:10.14739/2310-1237.2016.3.87505

Authors

M. Yu. Kolesnyk Zaporizhzhia State Medical University,
O. V. Nikityuk University Clinic of Zaporizhzhia State Medical University,
O. V. Komarova-Laz’ko University Clinic of Zaporizhzhia State Medical University,
S. N. Gulevskij University Clinic of Zaporizhzhia State Medical University,
A. M. Kiosov University Clinic of Zaporizhzhia State Medical University,

DOI:

https://doi.org/10.14739/2310-1237.2016.3.87505

Keywords:

Myxoma, Tuberculosis, Left Atrium, Transesophageal Echocardiography

Abstract

The symptoms and syndromology of myxomas with clinical features of a rare comorbidity – lung tuberculosis and left atrial myxoma in a 69-old year woman, are described in the article. The description includes the clinical history, transesophageal echocardiography findings, pathomorphological characteristics of myxoma, also photoillustrations of tumor’s macro- and microstructures. The analysis reflects the troubles in differential diagnosis of the clinical case due to non-specific symptoms of both diseases. The discussion provides the information about the possible pathophysiological link between myxoma and tuberculosis and the role of interleukin6 inthis process.

References

Cohen, R., Singhb, G., Menab, D., Garciac, C. A., Loarteb, P., & Mirrera, B. (2012). Atrial myxoma: a case presentation and review. Cardiol Res, 3(1), 41–44.

Bruce, C. J. (2011). Cardiac tumours: diagnosis and management. Heart, 97(2), 151–160. doi:10.1136/hrt.2009.186320.

Wang, J. G., Li, Y. J., Liu, H., Li, N. N., Zhao, J., & Xing, X. M. (2012). Clinicopathologic analysis of cardiac myxomas: seven years’ experience with 61 patients. J Thorac Dis, 4(3), 272–283. doi: 10.3978/j.issn.2072-1439.2012.05.07.

Yuan, S. M. (2012). Mitral valve myxoma: clinical features, current diagnostic approaches, and surgical management. Cardiol J., 19(1), 105–109. doi: 10.5603/CJ.2012.0019. •

Volz, M. S., Loddenkemper, C., Morguet, A., Moos, V., & Schneider, T. (2015). Cardiac myxoma secreting interleukin-6 promotes cavitary tuberculosis: a case report. Int J Tuberc Lung Dis, 19(10), 1265–1266. doi: 10.5588/ijtld.15.0405.

Dutta, R. K., Kathania, M., Raje, M., & Majumdar, S. (2012). IL-6 inhibits IFN-γ induced autophagy in Mycobacterium tuberculosis H37Rv infected macrophages. Int J Biochem Cell Biol, 44(6), 942–954. doi: 10.1016/j.biocel.2012.02.021.

Kuroki, S., Naitoh, K., Katoh, O., Yamada, H., & Itoh, T. (1992). Increased interleukin-6 activity in cardiac myxoma with mediastinal lymphadenopathy. Intern Med, 31(10), 1207–1209.