Eechinococcosis of the soft tissues of the thigh

Authors

DOI:

https://doi.org/10.14739/2310-1237.2025.3.332369

Keywords:

echinococcosis, parasitic invasion, diagnosis, morphology, treatment

Abstract

Aim: to analyse a clinical case of echinococcosis of rare localisation – in the soft tissues of the thigh, taking into account the diagnostic tactics used and an individualised approach to antiparasitic treatment.

Materials and methods. The medical records of patient S., 38 years old, who underwent hospital treatment and subsequent long-term outpatient observation for echinococcosis during 2022–2024 at the Medical Educational and Scientific Center “University Clinic” of Zaporizhzhia State Medical and Pharmaceutical University were analysed.

Results. The study demonstrates the clinical observation of an extremely rare variant of Echinococcus granulosus cyst localisation in the subcutaneous tissue of the thigh. An integrated approach to the diagnosis of echinococcosis using serological, pathomorphological, and various imaging methods made it possible to identify the presence of a combined lesion. Taking into account the multiple localisation of echinococcal cysts, the patient’s treatment approach included surgical removal of the cyst from the subcutaneous tissue of the right thigh and long-term conservative drug treatment with albendazole, considering the small size of the echinococcal cyst in the right lung. Based on the results of seronegativity and calcification of the cyst in the lung, albendazole therapy was discontinued.

Conclusions. This clinical example confirms the need for a comprehensive diagnostic approach to the verification of rare and multiple locations of Echinococcus granulosus cysts and individualised treatment.

Author Biographies

O. A. Svitlytska, Zaporizhzhia State Medical and Pharmaceutical University

PhD, Head of Multimodal Pathology Department, Educational and Scientific Medical Center “University Clinic”

O. V. Riabokon, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, DSc, Professor, Head of the Department of Infectious Diseases

V. O. Tumanskyi, Zaporizhzhia State Medical and Pharmaceutical University

MD, PhD, DSc, Professor of the Department of Pathological Anatomy and Forensic Medicine, Zaporizhzhia State Medical and Pharmaceutical University, Honored Science and Technology Figure of Ukraine

V. V. Onyshchenko, Zaporizhzhia State Medical and Pharmaceutical University

Head of the Pathohistology Laboratory, Educational and Scientific Medical Center “University Clinic”

T. A. Kuchuhurna, Medical Center “Unimed”, Zaporizhzhia

Doctor of Ultrasound Diagnostics

References

Wen H, Vuitton L, Tuxun T, Li J, Vuitton DA, Zhang W, et al. Echinococcosis: Advances in the 21st Century. Clin Microbiol Rev. 2019;32(2):e00075-18. doi: https://doi.org/10.1128/CMR.00075-18

Casulli A. New global targets for NTDs in the WHO roadmap 2021-2030. PLoS Negl Trop Dis. 2021;15(5):e0009373. doi: https://doi.org/10.1371/journal.pntd.0009373

Akimniyazova B, Kausova G, Yeshmuratov T, Toksanbayev D, Esetova G. Practice of Surgical Treatment for Patients with Combined Echinococcosis of Chest and Abdominal Organs. Tanaffos. 2021;20(2):140-9.

Caushi F, Hysa E, Skenduli I, Lisha L, Hatibi A, Bica L, et al. A rare and challenging case of intrapericardial hydatidosis. J Cardiothorac Surg. 2023;18(1):336. doi: https://doi.org/10.1186/s13019-023-02455-3

Hassini L, Mhiri A, Aloui Y, Maitigue MB, Mtaoumi M, Bouattour K. Isolated Muscular Echinococcosis of the Hand and Forearm: A Case Report. J Orthop Case Rep. 2024;14(9):136-40. doi: https://doi.org/10.13107/jocr.2024.v14.i09.4756

Samsami M, Qaderi S, Zebarjadi Bagherpour J, Lucero-Prisno DE 3rd. A case report of primary isolated extrahepatic hydatid cyst of the soft tissues of the breast and thigh. Int J Surg Case Rep. 2021;79:475-8. doi: https://doi.org/10.1016/j.ijscr.2021.01.087

Khan H, Casulli A, Harandi MF, Afzal MS, Saqib MA, Ahmed H. A Retrospective Cohort Study on Human Cystic Echinococcosis in Khyber Pakhtunkhwa Province (Pakistan) Based on 16 Years of Hospital Discharge Records. Pathogens. 2022;11(2):194. doi: https://doi.org/10.3390/pathogens11020194

Kosmidis CS, Papadopoulos K, Mystakidou CM, Sevva C, Koulouris C, Varsamis N, et al. Giant Echinococcosis of the Liver with Suppuration: A Case Report and Review of the Literature. Medicina (Kaunas). 2023;59(6):1070. doi: https://doi.org/10.3390/medicina59061070

WHO Informal Working Group. International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop. 2003;85(2):253-61. doi: https://doi.org/10.1016/s0001-706x(02)00223-1

Tamarozzi F, Deplazes P, Casulli A. Reinventing the Wheel of Echinococcus granulosus sensu lato Transmission to Humans. Trends Parasitol. 2020;36(5):427-34. doi: https://doi.org/10.1016/j.pt.2020.02.004

Machboua A, Elhani FZ, Marouf R. Intra thoracic extra pulmonary hydatidosis: prognosis and outcomes of 8 operated patients. J Cardiothorac Surg. 2023;18(1):24. doi: https://doi.org/10.1186/s13019-023-02115-6

Kelchev A, Kunev B, Partenova A, Genova K, Nikolov D. Cardiac echinococcosis, a multidisciplinary approach in the diagnosis and treatment of this rare entity: two case reports and literature review. Folia Med (Plovdiv). 2023;65(2):336-42. doi: https://doi.org/10.3897/folmed.65.e79066

Şimşek S. Hydatid cyst in the teres major muscle and brain. Rev Soc Bras Med Trop. 2022;55:e03172022. doi: https://doi.org/10.1590/0037-8682-0317-2022

Kurz K, Schwabegger A, Schreieck S, Zelger B, Weiss G, Bellmann-Weiler R. Cystic echinococcosis in the thigh: a case report. Infection. 2019;47(2):323-9. doi: https://doi.org/10.1007/s15010-018-1255-9

Farooq SM, Liu W. Intrabiliary rupture of hepatic echinococcosis. Radiol Infect Dis. 2022;9(4):145-51. doi: https://doi.org/10.4103/rid.rid_46_22

Buscemi C, Randazzo C, Buscemi P, Caldarella R, Lombardo M, Buscemi S. Very Prolonged Treatment with Albendazole of a Case of Disseminated Abdominal Cystic Echinococcosis. Trop Med Infect Dis. 2023;8(9):449. doi: https://doi.org/10.3390/tropicalmed8090449

Mihmanli M, Idiz UO, Kaya C, Demir U, Bostanci O, Omeroglu S, et al. Current status of diagnosis and treatment of hepatic echinococcosis. World J Hepatol. 2016;8(28):1169-81. doi: https://doi.org/https://doi.org/10.4254/wjh.v8.i28.1169

Stojkovic M, Zwahlen M, Teggi A, Vutova K, Cretu CM, Virdone R, et al. Treatment response of cystic echinococcosis to benzimidazoles: a systematic review. PLoS Negl Trop Dis. 2009;3(9):e524. doi: https://doi.org/10.1371/journal.pntd.0000524

Additional Files

Published

2025-12-23

How to Cite

1.
Svitlytska OA, Riabokon OV, Tumanskyi VO, Onyshchenko VV, Kuchuhurna TA. Eechinococcosis of the soft tissues of the thigh. Pathologia [Internet]. 2025Dec.23 [cited 2026Feb.11];22(3):251-6. Available from: https://pat.zsmu.edu.ua/article/view/332369

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Section

Case Reports