Clinical and pathogenetic differences of the course of flow nonalcoholic steatohepatitis in obese patients with and without hypertension

Authors

  • O.S. Khukhlina Bukovina State Medical University, Chernivtsi, Ukraine,
  • O.E. Mandryk Bukovina State Medical University, Chernivtsi, Ukraine,
  • A.A. Antoniv Bukovina State Medical University, Chernivtsi, Ukraine,

DOI:

https://doi.org/10.14739/2310-1237.2013.2.17800

Keywords:

nonalcoholic steatohepatitis, obesity, hypertension

Abstract

The article is devoted to the study of clinical and pathogenetic peculiarities of nonalcoholic steatohepatitis, a condition of components of connective tissue, metabolic intoxication, hemostasis and fibrinolysis by comorbidity with and without stage II hypertension. It was found that in the course of comorbid nonalcoholic steatohepatitis with hypertension and obesity compared with nonalcoholic steatohepatitis  without hypertension there is a higher intensity of hemostasiological disorders.

References

Успенский Ю.П. Метаболический синдром и неалкогольныйстеатогепатит: причинно-следственный континуум / Ю.П.Успенский, Е.В.Балукова // Гастроэнтерол. – 2009. – №1. – С. 43–46.

Харченко Н.В. Неалкогольныйстеатогепатиткакпроявлениеметаболическогосиндрома. Современныеподходы к лечению / Н.В. Харченко, Е.В. Родонежская // Новости мед. и фармации. – 2007. – Тем. номер «Гастроэнтерология», №226. – С. 18–19.

Хухліна О.С. Неалкогольна жирова хвороба печінки та інсулінорезистентність: патогенез, клініка, діагностика, лікування глутаргіном / О.С.Хухліна, М.Ю.Коломоєць. – Чернівці, 2008. – 318с.

Bohinc B.N. Mechanisms of Disease Progression in NASH: New Paradigms / B.N.Bohinc, A.M.Diehl // Clin.LiverDis. – 2012. – Vol.16, №3. –Р. 549–565.

Fujii H. Inflammation and fibrogenesis in steatohepatitis /H.Fujii, N.Kawada // J.Gastroenterol. – 2012. – Vol.47, №3. – P. 215–225.

NASH isanInflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications / Farrell G.C., van Rooyen D., Gan L., Chitturi S. // GutLiver. – 2012. – Vol.6, №2. – P.149–171.

Targher G. Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: the plotthickens / G. Targher // Diabet. Med. – 2007. –Vol.24, №1. – P.1–6.

Torres D.M. Features, diagnosis, and treatment of nonalcoholic Fatty liver disease / Torres D.M., Williams C.D., Harrison S.A. // Clin.Gastroenterol.Hepatol. – 2012. – Vol.10, №8. –P. 837–858.

Downloads

How to Cite

1.
Khukhlina O, Mandryk O, Antoniv A. Clinical and pathogenetic differences of the course of flow nonalcoholic steatohepatitis in obese patients with and without hypertension. Pathologia [Internet]. 2013Sep.30 [cited 2024Nov.2];(2). Available from: http://pat.zsmu.edu.ua/article/view/17800

Issue

No. 2 (2013)

Section

Original research

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Лицензия Creative Commons
    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).