Features of kidney affection in the conditions of highly active antiretroviral therapy in patients with HIV/AIDS

Authors

  • E.V. Ryabokon Zaporizhzhya State Medical University, Ukraine,
  • T.E. Onishenko Zaporizhzhya State Medical University, Ukraine,
  • E.L. Koltunik Zaporizhzhya State Medical University, Ukraine,

DOI:

https://doi.org/10.14739/2310-1237.2013.2.17810

Keywords:

HIV-infection, highly active antiretroviral therapy, kidney affection

Abstract

As a result of the analysis of 330 archival patient’s cards of patients with HIV/AIDS who received highly active antiretroviral therapy with the inclusion of tenofovir in the treatment scheme, kidney affection has been fixed in 1,5 % of cases only in patients with the acquired immunodeficiency syndrome, accompanying chemotherapy concerning tuberculosis and/or pneumocystosis, existence of other background somatic pathology.

References

Global report: UNAIDS report on the global AIDSepidemic 1010 [електронний ресурс] / UNAIDS // WHO Library. – 2010. – 364 p. – Режим доступу: http://www.unaids.org/globalreport/

A shift of the endothelial dysfunction markers in patients with HIV-infection.AIDS under HAART / V.D. Moskaliuk, V.D. Sorokhan, S.R. Melenko et al. // Інфекційні хвороби. – 2013. – №2 (72). – С. 26–28.

Андросова О.С. Морфофункціональні зміни стану печінки при синдромі набутого імунодефіциту людини: автореф. дис. ... к. мед. н. / Андросова О.С. – К., 2013. – 21 с.

Патоморфологія печінки у ВІЛ-інфікованих пацієнтів / Н.В. Матієвська, В.М. Циркунов, Н.І. Прокопчик [та ін.] // Інфекційні хвороби. – 2012. – №3 (69). – С. 15–23.

Human immunodeficiency virus infection and kidney transplantation in the era of highly active antiretroviral therapy and modern immunosuppression / K.C. Abbott, S.J. Swanson, L.Y. Agodoa [et al.] // J. Am. S. Nephrol. – 2004. – Vol. 15. – P. 1633–1639.

Rho M. Nephrotoxicity associated with antiretroviral therapy in HIV infected patients / M. Rho, M.A. Perazella // Curr. Drug. Saf. – 2007. – Vol. 2. – P. 147–154.

Wyatt C.M. Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality / C.M. Wyatt // AIDS. – 2006. – Vol. 20 (4). – P. 561–565.

Бартлетт Д. Клинические аспекты ВИЧ-инфекции / Д. Бартлетт, Д. Галлант, П. Фам. – М.: Р.Валент, 2012. – 528 с.

Юрин О.Г. Первый опыт применения тенофовира при лечении больных ВИЧ-инфекцией в России / О.Г. Юрин, М.Д. Голиусова, М.О. Деулина [и соавт.] // Эпидемиология и инфекционные болезни. – 2013. – №1. – С. 62–69.

Fanconi syndrome and renal failure induced by tenofovir: a first case report / D. Verhelst, M. Monge, J.L. Meynard [et al.] // Am. J. Kidney Dis. – 2002. – Vol. 40 (6). – P. 1331–1333.

Horberg M. Impact of tenofovir on renal function in HIV-infected, antiretroviral-naive patients / M. Horberg, B. Tang, W. Towner [et al.] // J. Acquir. Immune. Defic. Syndr. – 2010. – Vol. 53. – P. 62–69.

Jones R. Renal dysfunction with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy regimens is not observed more frequently: a cohort and case-control study / R. Jones // J. Acquir. Immune. Defic. Syndr. – 2004. – Vol. 37. – P. 1489–1495.

Нефротоксические эффекты высокоактивной антиретровирусной терапии / Н.Д. Ющук, Г.В. Волгина, Н.А. Томилина [и соавт.] // Нефрология и диализ. – 2010. – №3. – С. 154–163.

Tenofovir-associated acute and chronic kidney disease: a case of multiple drug interactions / A.E. Zimmermann, T. Pizzoferrato, J.Bedford [et al.] // Clin. Infect. Dis. – 2006. – Vol. 42 (2). – P. 283–290.

How to Cite

1.
Ryabokon E, Onishenko T, Koltunik E. Features of kidney affection in the conditions of highly active antiretroviral therapy in patients with HIV/AIDS. Pathologia [Internet]. 2013Sep.30 [cited 2024Nov.23];(2). Available from: http://pat.zsmu.edu.ua/article/view/17810

Issue

Section

Original research