Persistent genital arousal disorder: clinical, differential diagnostic and care aspects (clinical report)

Authors

DOI:

https://doi.org/10.14739/2310-1237.2023.1.270216

Keywords:

PGAD, diagnosis, treatment, care, clinical report

Abstract

Persistent genital arousal disorder (PGAD) is a condition of persistent genital arousal, in the absence of a psychological component and organic pathology from the vascular, endocrine and nervous system.

The aim of the study is to examine the symptoms, clinical picture, developmental dynamics, risk factors, and treatment for PGAD.

Materials and methods. The clinical case of observation of PGAD in a 20-year-old female patient suffering from recurrent depressive disorder is presented. Methods included in clinical, psychopathological and psychodiagnostic examination have been with using the following techniques: Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Visual Analogue Scales of pain intensity (VAS).

Results. As a result of collection of life and disease history, analysis of examination findings by related specialists and additional research methods of patient with PGAD the next diagnosis has been made according to the International Classification of Diseases 10th Revision: Recurrent depressive disorder, current episode of moderate severity with somatic symptoms (F33.11). She has been treated with a number of drugs from the Selective serotonin reuptake inhibitors group and mood stabilizers, the combination of sertraline and lamotrigine appeared the optimal treatment option. The results of the treatment have been satisfactory, the symptoms of PGAD have stopped bothering the patient, the emotional state has improved significantly.

Conclusions. The case of the PGAD is presented. Clinical picture of the case turned out to be typical in comparison with the results of other researchers. The peculiarity is the possible association of symptoms with withdrawal of escitalopram. The case confirms the data upon the high suicidal risk in this disorder. The patient’s treatment requires intervention of different medical specialists to rule out organic pathology and using of multidisciplinary approach. Sertraline and lamotrigine appeared effective in the treatment of PGAD.

Author Biographies

V. V. Ogorenko, Dnipro State Medical University, Ukraine

MD, PhD, DSc, Professor of the Department of Psychiatry, Narcology and Medical Psychology

A. H. Kyrychenko, State Institution “Ukrainian State Research Institute of Medical and Social Disability Problems of the Ministry of Health of Ukraine”, Dnipro

MD, PhD, DSc, Professor, Director

T. Y. Shusterman, Dnipro State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of Psychiatry, Narcology and Medical Psychology

V. O. Kokashynskyi, Dnipro State Medical University, Ukraine

MD, Assistant of the Department of Psychiatry, Narcology and Medical Psychology

N. V. Tomakh, State Institution “Ukrainian State Research Institute of Medical and Social Disability Problems of the Ministry of Health of Ukraine”, Dnipro

MD, PhD, Medical Director

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Published

2023-04-28

How to Cite

1.
Ogorenko VV, Kyrychenko AH, Shusterman TY, Kokashynskyi VO, Tomakh NV. Persistent genital arousal disorder: clinical, differential diagnostic and care aspects (clinical report). Pathologia [Internet]. 2023Apr.28 [cited 2024Mar.1];20(1):94-8. Available from: http://pat.zsmu.edu.ua/article/view/270216

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Case Reports