Stromal-vascular fraction of adipose tissue using in the repair of distal biceps tendon tears




stromal vascular fraction, tendon injuries, biceps brachii muscle, surgical procedures


Distal biceps tendon rupture is most commonly found in working-age men, making the treatment terms and functional recovery level of significant socio-economic importance. Modern scientific research aims to minimize the number of complications, particularly recurrent ruptures. Attention is drawn to modern technologies aimed at stimulating regenerative processes, including the use of the stromal vascular fraction (SVF) of abdominal adipose tissue. The article presents the results of the practical application of SVF in the surgical restoration of the distal biceps tendon of the shoulder.

The aim of the study: to improve the results of surgical treatment of distal biceps tendon rupture, shorten recovery times and reduce the incidence of complications using stromal vascular fraction obtained from adipose tissue.

Materials and methods. The study was carried out by evaluating the results of surgical restoration of the distal biceps tendon in 34 patients who were divided into 2 groups – with intraoperative introduction of SVF at the reattachment site (n = 14) and without it (n = 20). At follow-up examinations after 3 days, 2 weeks, 6 weeks, and 3 months, the results of the patients were evaluated using the VASH, DASH scales and the range of motion in the affected elbow joint was measured. In addition, a general blood analysis and quantitative determination of C-reactive protein were performed before the operation and at follow-up visits.

Results. There was no difference in the level of C-reactive protein and the general blood analysis score between patients in both groups at all study time points. It was found that after 2 weeks, the VAS score was significantly lower in the study group. The DASH score on follow-up examinations after 2 and 6 weeks was significantly better in the study group. Also, at follow-up examinations after 2 and 6 weeks, a greater volume of supination movements was observed in the study group.

Conclusions. The using of SVF did not lead to the development of postoperative complications. The using of SVF allowed the reduction of the recovery time and decreased in the incidence of complications, as well as improved functional outcomes.

Author Biographies

M. S. Lisunov, Zaporizhzhia State Medical University, Ukraine

Senior laboratory technician of the Department of Orthopedics and Traumatology

M. L. Holovakha, Zaporizhzhia State Medical University, Ukraine

MD, PhD, DSc, Professor, Head of the Department of Orthopedics and Traumatology

M. O. Kozhemiaka, Zaporizhzhia State Medical University, Ukraine

MD, PhD, Associate Professor of the Department of Traumatology and Orthopedics


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How to Cite

Lisunov MS, Holovakha ML, Kozhemiaka MO. Stromal-vascular fraction of adipose tissue using in the repair of distal biceps tendon tears. Pathologia [Internet]. 2023Apr.28 [cited 2024Apr.21];20(1):50-7. Available from:



Original research