Fibromuscular dysplasia of internal carotid artery

Authors

  • Yu. I. Kuzyk

DOI:

https://doi.org/10.14739/2310-1237.2015.1.42829

Keywords:

Fibromuscular Dysplasia, Carotid Artery Disease, Microscopy, Clinical Trial

Abstract

Fibromuscular dysplasia (FMD) is the disease of arteries of medium and small caliber with unknown etiology.

Aim. To determine the features of pathomorphological picture of carotid FMD operating material of 134 patients operated on for symptomatic FMD was studied using methods of light microscopy and histochemical methods.

Methods and results. It was established that specific macroscopic feature of FMD of carotid arteries are multiple saccular aneurysms, creating a picture of the «string of beads». A typical pathomorphological variant of FMD is medial fibroplasia with total fibro-muscular transformation and complete loss of elastic.

Conclusion. This indicates that FMD is a non-inflammatory disease, based on the muscular and connective tissue transformation, probably of congenital genesis.

References

Kuzyk, Yu. I. (2006) Fibromyshechnaya displaziya arterij [Arterial fibromuscular dysplasia]. Archiv patologii, 4(68), 57–61. [in Russian].

La Barbera, G., La Marca, G., Cappello, F., & Valentino, F. (2006) Anomalies of the extracranial internal carotid artery: anatomo-clinical and histologic study. International Angiology, 25(2), 145.

Begelman, S. M., & Olin, J. W. (2000) Fibromuscular dysplasia. Current Opin Rheumatology, 12, 41–47.

Stahfeld, K., Maens, J., & Didomenico, P. (2007) Сarotid artery fibromuscular dysplasia. American Journal of Surgery, 193(1), 71–72.

Zhou, W., Bush, R. L., Lin, P. l., Lumsted, A. B., & Kougias S. (2005) Fibromuscular dysplasia of the carotid artery. Journal American College of Surgery, 200, 807.

Van Damme, H., Sakalihasan, N., & Limet, R. (1999) Fibromuscular dysplasia of the internal carotid artery: personal experience with 13 cases and literature review. Acta Chirurgia Belglium, 99, 163–168.

Kirton, A., Crone, M., Benseler, S., Mineyko, A., Armstrong, D., Wade, A., et al. (2013) Fibromuscular dysplasia and childhood stroke. Brain, 136, 1846–1856. doi: 10.1093/brain/awt111.

Nader-Kawachi, Ju., Anaya-Santacriz, E., Penaherrera-Oviedo, C., Andrade-Magdaleno, M., Alva, L. F., & Chable-Montero, F. C. (2014) Intimal fibromuscular dysplasia of the carotid artery: case report and review. International Journal of Stroke Research, 2(1), 1–5. doi:10.5923/j.stroke.20140201.01.

Olin, J. W. (2007) Reconizing and managing fibromuscular dysplasia. Cleveland Clinical Journal of Medicine, 74, 273–82.

Slovut, D. P., & Olin, J. F. (2004) Fibromuscular dysplasia. New England Journal of Medicine, 350, 1862–1871.

How to Cite

1.
Kuzyk YI. Fibromuscular dysplasia of internal carotid artery. Pathologia [Internet]. 2015May19 [cited 2024Nov.24];(1). Available from: http://pat.zsmu.edu.ua/article/view/42829

Issue

Section

Original research