Fibromuscular dysplasia of internal carotid artery

Authors

  • Yu. I. Kuzyk

DOI:

https://doi.org/10.14739/2310-1237.2015.1.42829

Keywords:

Fibromuscular Dysplasia, Carotid Artery Disease, Microscopy, Clinical Trial

Abstract

Fibromuscular dysplasia (FMD) is the disease of arteries of medium and small caliber with unknown etiology.

Aim. To determine the features of pathomorphological picture of carotid FMD operating material of 134 patients operated on for symptomatic FMD was studied using methods of light microscopy and histochemical methods.

Methods and results. It was established that specific macroscopic feature of FMD of carotid arteries are multiple saccular aneurysms, creating a picture of the «string of beads». A typical pathomorphological variant of FMD is medial fibroplasia with total fibro-muscular transformation and complete loss of elastic.

Conclusion. This indicates that FMD is a non-inflammatory disease, based on the muscular and connective tissue transformation, probably of congenital genesis.

References

Kuzyk, Yu. I. (2006) Fibromyshechnaya displaziya arterij [Arterial fibromuscular dysplasia]. Archiv patologii, 4(68), 57–61. [in Russian].

La Barbera, G., La Marca, G., Cappello, F., & Valentino, F. (2006) Anomalies of the extracranial internal carotid artery: anatomo-clinical and histologic study. International Angiology, 25(2), 145.

Begelman, S. M., & Olin, J. W. (2000) Fibromuscular dysplasia. Current Opin Rheumatology, 12, 41–47.

Stahfeld, K., Maens, J., & Didomenico, P. (2007) Сarotid artery fibromuscular dysplasia. American Journal of Surgery, 193(1), 71–72.

Zhou, W., Bush, R. L., Lin, P. l., Lumsted, A. B., & Kougias S. (2005) Fibromuscular dysplasia of the carotid artery. Journal American College of Surgery, 200, 807.

Van Damme, H., Sakalihasan, N., & Limet, R. (1999) Fibromuscular dysplasia of the internal carotid artery: personal experience with 13 cases and literature review. Acta Chirurgia Belglium, 99, 163–168.

Kirton, A., Crone, M., Benseler, S., Mineyko, A., Armstrong, D., Wade, A., et al. (2013) Fibromuscular dysplasia and childhood stroke. Brain, 136, 1846–1856. doi: 10.1093/brain/awt111.

Nader-Kawachi, Ju., Anaya-Santacriz, E., Penaherrera-Oviedo, C., Andrade-Magdaleno, M., Alva, L. F., & Chable-Montero, F. C. (2014) Intimal fibromuscular dysplasia of the carotid artery: case report and review. International Journal of Stroke Research, 2(1), 1–5. doi:10.5923/j.stroke.20140201.01.

Olin, J. W. (2007) Reconizing and managing fibromuscular dysplasia. Cleveland Clinical Journal of Medicine, 74, 273–82.

Slovut, D. P., & Olin, J. F. (2004) Fibromuscular dysplasia. New England Journal of Medicine, 350, 1862–1871.

Downloads

How to Cite

1.
Kuzyk YI. Fibromuscular dysplasia of internal carotid artery. Pathologia [Internet]. 2015May19 [cited 2024Apr.25];(1). Available from: http://pat.zsmu.edu.ua/article/view/42829

Issue

No. 1 (2015)

Section

Original research

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Лицензия Creative Commons
    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).