The level of the autoantibodies to antigenes of the thyroid gland at metabolic syndrome with deficiency of estrogens and the hypothyroidism
DOI:
https://doi.org/10.14739/2310-1237.2012.2.16759Keywords:
deficiency of estrogens, metabolic syndrome, hypothyroidism, autoantibodies, 17β-estradiolAbstract
It has been shown that the concentration of autoantibodies to thyroperoxidase was significantly increased in rats with estrogen-deficiency. The combination of hypoestrogenia and metabolic syndrome with hypothyroidism intensified destructive processes in the thyroid gland. 17β-estradiol had the protective effect to the damaged thyroid gland in ovarioectomized animals with metabolic syndrome and hypothyroidism that was confirmed by significant reduction of concentration of autoantibodies to thyroperoxidase.References
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