Features of expression of protein Claudin 11 at various forms of male infertility

Authors

  • S. V. Bazalytska
  • A.M. Romanenko
  • Yu. V. Persidsky

DOI:

https://doi.org/10.14739/2310-1237.2012.3.16986

Keywords:

male infertility, protein Claudin 11

Abstract

Immunohistochemical features of an expression of  protein Claudin 11 in testicular tissue of 28 patients with excretory-obstructive and secretory forms of male infertility  are studied. Significant decrease of  protein Claudin 11 IHC expression level at the secretory form of male infertility and at syndrome «only Sertoli cells» is revealed in comparison with excretory-obstructive form of male infertility. Results testify to considerable disturbances of blood-testis barrier, which have become the basis of the development of additional immune component and intensification of pathological changes in patients with the secretory form of male infertility.

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How to Cite

1.
Bazalytska SV, Romanenko A, Persidsky YV. Features of expression of protein Claudin 11 at various forms of male infertility. Pathologia [Internet]. 2013Aug.29 [cited 2024Nov.26];(3). Available from: http://pat.zsmu.edu.ua/article/view/16986

Issue

Section

Original research