An 8-month old with Erythema nodosum – clinical case report, literature review

Authors

  • S. N. Nedelska
  • O. P. Pakholchuk

DOI:

https://doi.org/10.14739/2310-1237.2015.2.51161

Keywords:

Erythema nodosum, Children, Food Allergy, Specific IgE, Gluten

Abstract

Erythema nodosum is rare pathology in childhood and usually associated with big antigen load.

Aim of the work was to make differential analysis of the described case with developed multiple, nontender, depth erythematose papules in the epidermis-dermis (like nodules) on the head, trunk, extremities, associated with adopted cow's milk-based formula intake.

Methods and results. The next methods, as deep literature review and differential analysis, helped to underline probable pathogenetic mechanisms of such type of allergy skin symptoms, to diagnose Erythema nodosum in the child.

Conclusion. This clinical case showed presence of rare clinical food allergy skin symptoms that have mixed mechanisms of onset. Further studies of the gear of onset and histology specificity are needed.

References

Bogadel`nikov, I. V. (2009) Differencial`nyj diagnoz infekcionnykh boleznei u detej [Differential diagnosis of the infectious diseases in children]. Simpheropol`. [in Ukrainian].

Abek, D., Burgdorf, W. & Kraemer, H. (2007) Bolezni kozhi u detej [Common skin diseases in children]. Moskow: Medicinskaya literatura [in Russian].

Uchajkin, V. F., Nisevich, N. I. & Shamsheva, O. V. (2007) Infekcionnye bolezni i vakcinoprophilaktika u detej [Infectious diseases and vaccinoprophylaxis in children]. Moskow: GE`OTAR-Media. [in Russian].

Chern, E., Yau, D., & Ho, J. (2010) Generalized eruptive histiocytosis in an infant. Acta Derm Venereol, 90(2), 204–5. doi: 10.2340/00015555-0805.

Requena, L. & Requena, C. (2002) Erythema Nodosum. Dermatology Online Journal, 8(1), 4. Retrieved from https://escholarship.org/uc/item/4829t6rn.

Gilchrist, H. & Patterson, J. W. (2013) Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management. Dermatologic Therapy, 23(4), 320–327. doi: 10.1111/j.1529-8019.2010.01332.x.

Habif, T., Campbell, J., Chapman, S., Dinulos, J. & Zug, K. (2011) Skin Disease: Diagnosis and Treatment. Philadelphia: PA: Elsevier/Saunders. Retrieved from www.ncbi.nlm.nih.gov/pubmed/16872469.

Lamacchia, C., Camarca, A., Picascia, S., Di Luccia, A., & Gianfrani, C. (2014) Cereal-Based Gluten-Free Food: How to Reconcile Nutritional and Technological Properties of Wheat Proteins with Safety for Celiac Disease Patients. Nutrients, 6(2), 575–590. doi: 10.3390/nu6020575.

Kristjánsson, G., Venge, P, Hällgren, R (2007) Mucosal reactivity to cow's milk protein in coeliac disease. Clin Exp Immunol, 147(3),449–455.

Muraro, A, Werfel, T, Hoffmann-Sommergruber, K., Roberts, G., Beyer, K., Bindslev-Jensen, C., et al. (2014). EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy. Allergy, 69(8), 1008-1025. doi: 10.1111/all.12429.

Vojdani, A., Kharrazian, D., & Mukherjee, P. S. (2014) The Prevalence of Antibodies against Wheat and Milk Proteins in Blood Donors and Their Contribution to Neuroimmune Reactivities. Nutrients, 6(1), 15–36. doi: 10.3390/nu6010015.

Whelan, J. P. & Zembowicz, A. (2006) Case 19-2006: A 22-Month-Old Boy with the Rapid Growth of Subcutaneous Nodules. N Engl J Med, 354, 2697–704.

Zopf, Y., Hahn, E., Raithel, M., Baenkler, H.-W., & Silbermann, A. (2009) The Differential Diagnosis of Food Intolerance. Dtsch Arztebl Int., 106(21), 359–370. doi: 10.3238/arztebl.2009.0359.

Downloads

How to Cite

1.
Nedelska SN, Pakholchuk OP. An 8-month old with Erythema nodosum – clinical case report, literature review. Pathologia [Internet]. 2015Oct.8 [cited 2024Nov.8];(2). Available from: http://pat.zsmu.edu.ua/article/view/51161

Issue

No. 2 (2015)

Section

To a practitioner

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Лицензия Creative Commons
    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).